Treatment with the non-selective dopamine agonist pergolide caused a significant reduction of serum PRL concentration with a remarkable decrease of body weight.
During follow-up, repeat MRI scan revealed disappearance of the microadenoma. The reduction of the daily dose of pergolide was associated with an increase of serum PRL with significant weight gain. More severe hypopituitarism can lead to hypothyroidism or abnormally low cortisol levels, causing:.
Your doctor will conduct a physical examination and ask you about your symptoms and medical history. A blood test measures the level of prolactin, which is essential for establishing a diagnosis. A very high level indicates a prolactinoma, whereas a mildly elevated level may indicate:.
Certain medications and conditions may mildly elevate prolactin levels, and therefore must be considered before making the diagnosis of prolactinoma:. Diagnosing a prolactinoma requires special care, expertise and specialized laboratory equipment.
An experienced pituitary tumor team understands the nuances of the diagnostic procedure. We will occasionally need to run extra tests and procedures if there are concerns about the results.
Most prolactinomas can be detected using magnetic resonance imaging MRI of the pituitary gland. We use a special MRI pituitary protocol in order to best visualize the tumor. Medication is the first line of treatment for a prolactinoma. Your doctor will prescribe a medication that mimics the effects of dopamine, the brain chemical that normally inhibits the release of prolactin by the pituitary gland.
The two most commonly prescribed medications are:. About 75 percent of patients respond to medical therapy, with a noticeable reduction in tumor size:. Sometimes, the tumor does not respond to medication, or you cannot tolerate the medicine, perhaps due to unwanted side effects.
In this case, your doctor may recommend surgical removal of the tumor. Your overall aim is to be healthy and reduce your calorie intake.
As such, you need to start or increase your exercise programme. If you are just starting your exercise programme, it is best to start slowly at first and then gradually increase as you go along. Now you can read the Jamaica Observer ePaper anytime, anywhere. Subscribe Login. Dear Donovan, I hope you will be able to assist me with this concern.
I look forward to your response. Some comments may be republished on the website or in the newspaper; email addresses will not be published. Please understand that comments are moderated and it is not always possible to publish all that have been submitted. We will, however, try to publish comments that are representative of all received. We ask that comments are civil and free of libellous or hateful material. University of Gothenburg. Hormone Prolactin Reduces Fat Metabolism.
Retrieved November 10, from www. Results show that the team created a new mouse breed, called NSG-Pro, The authors of the study propose that 12,diHOME, as well as linked pathway metabolites from breast milk, have a protective effect
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