If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from freezing and keep it out of the reach of children. Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses.
Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome.
Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention. Stop taking the medication and seek immediate medical attention if any of the following occur:. J Am Soc Nephrol. Upper gastrointestinal tract injury in patients receiving kayexalate sodium polystyrene sulfonate in sorbitol: clinical, endoscopic, and histopathologic findings.
Am J Surg Pathol. Intestinal necrosis due to sodium polystyrene Kayexalate in sorbitol enemas: clinical and experimental support for the hypothesis. Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate Kayexalate in sorbitol: an underrecognized condition.
Rashid A, Hamilton SR. From hyperkalemia to ischemic colitis: a resinous way. Clin Gastroenterol Hepatol. Ion-exchange resins for the treatment of hyperkalemia: are they safe and effective? Do not use in patients who do not have normal bowel function.
This includes postoperative patients who have not had a bowel movement post surgery. Do not use in patients who are at risk for developing constipation or impaction including those with history of impaction, chronic constipation, inflammatory bowel disease, ischemic colitis, vascular intestinal atherosclerosis, previous bowel resection, or bowel obstruction Discontinue use in patients who develop constipation.
Do not administer repeated doses in patients who have not passed a bowel movement. Clinical Questions Diseases 2. Kayexalate: What is it and does it work?
Commentary by Dr. Looking forward to your response. Please remember that you can count the number of cases of bowel necrosis associated with lactulose on your hand and the same level of evidence would suggest it is not as benign as you suggest:. Ned Tijdschr Geneeskd.
Pneumatosis coli following treatment with lactulose. N Y State J Med. Please read a great editoria 1: Braithwaite RS. A piece of my mind. There is no evidence that the peanut butter and jelly sandwich that brought for lunch today is going to satisfy me but I am sure it is. Lactulose is fine if you prefer, but please do something. Save my name, email, and website in this browser for the next time I comment.
Time limit is exhausted. All rights reserved. Disclaimer Website by Innov8 Place. February 2, Background: Hyperkalemia is the most common electrolyte disorder seen in the Emergency Department and treatment of hyperkalemia is core knowledge of EM training for interns and focuses on: 1 Stabilization of cardiac myocytes with calcium salts. Intervention: Oral or rectal cation exchange resin and a low or no potassium diet. The following two tabs change content below. Bio Latest Posts.
Latest posts by Anand Swaminathan see all. Hyperkalemia , kayexalate , Mythbuster. Like this article? Share on facebook Share on Facebook. Because sodium polystyrene sulfonate is not absorbed into the bloodstream, this medicine is not expected to be harmful during pregnancy or while nursing a baby.
Tell your doctor if you are pregnant or breast-feeding. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Avoid using antacids or laxatives without your doctor's advice.
Antacids or laxatives can make sodium polystyrene sulfonate less effective, or cause serious side effects. Do not use potassium supplements, calcium supplements, or salt substitutes while you are taking sodium polystyrene sulfonate, unless your doctor has told you to.
Avoid eating or drinking anything that contains sorbitol a fruit sugar often used as a sweetener in chewing gum, diet drinks, baked goods, or frozen desserts.
Use Kayexalate Sodium Polystyrene Sulfonate exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets.
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